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Pengertian Sitologi

Sitologi, lebih dikenal sebagai biologi sel, mempelajari struktur sel, komposisi seluler, dan interaksi sel dengan sel lain dan lingkungan yang lebih besar di mana mereka ada. Istilah “sitologi” juga dapat merujuk kepada Sitopatologi, yang menganalisis struktur sel untuk mendiagnosa penyakit.

Studi mikroskopis dan molekul sel dapat fokus pada organisme baik multisel atau bersel tunggal. Fakta bahwa kita sebagai manusia terdiri dari jutaan sel kecil, dan bahwa makhluk hidup lain di sekitar kita sama-sama dibentuk, sekarang hampir tidak membutuhkan penjelasan. Namun, konsep sel relatif baru. Komunitas ilmiah tidak menerima gagasan adanya sel sampai akhir abad ke-18.

Menyadari persamaan dan perbedaan sel adalah yang paling penting dalam sitologi. Pemeriksaan mikroskopis dapat membantu mengidentifikasi jenis sel. Melihat molekul yang membentuk seluler, kadang-kadang disebut biologi molekuler, membantu dalam deskripsi lebih lanjut dan identifikasi. Semua bidang biologi tergantung pada pemahaman struktur selular. Bidang genetika ada karena kita memahami struktur sel dan komponen.

Aspek penting lainnya dalam disiplin sitologi adalah memeriksa interaksi seluler. Dengan mempelajari bagaimana sel berhubungan dengan sel lain atau dengan lingkungan, ahli sitologi dapat memprediksi masalah atau memeriksa bahaya lingkungan sel, seperti zat beracun atau penyebab kanker. Pada manusia dan struktur multi-selular lainnya, sitologi dapat memeriksa kehadiran terlalu banyak dari satu jenis seluler, atau kurang cukupnya sel dari jenis tertentu. Dalam sebuah tes sederhana seperti hitung darah lengkap, laboratorium dapat melihat sel darah putih dan mengidentifikasi adanya infeksi, atau mungkin memeriksa tingkat rendah beberapa jenis sel darah merah dan mendiagnosa anemia.


Gangguan autoimun tertentu dapat didiagnosis dengan reaksi sel yang tidak normal. Tiroiditis Hashimoto, misalnya, adalah suatu kondisi autoimun yang disebabkan oleh reaksi sel abnormal. Alih-alih sel darah putih mengenali adanya sel-sel tiroid normal, antibodi ini menyerang mereka, menyebabkan tiroid rendah. Jika tidak diobati, kondisi ini dapat menyebabkan keterbelakangan, kelelahan ekstrim, obesitas, dan akhirnya kematian. Melalui sitologi, reaksi abnormal antibodi ini dapat dikenali, dan pengobatan dapat dilakukan jauh sebelum kondisi ini menciptakan masalah ireversibel.

Sitopatologi memiliki tujuan yang sama, tetapi cenderung mencari sel-sel yang tidak harus hadir dalam suatu organisme. Urinalisis dan tes darah, misalnya, dapat memindai adanya parasit atau bakteri yang dapat menyebabkan penyakit dan kematian. Oleh karena itu, dalam sitologi, pemahaman organisme bersel tunggal seperti berbagai bentuk bakteri adalah sama pentingnya dengan memahami struktur multi-selular.

pengertian Sitologi
Jenis sel manusia, yang semuanya dipelajari oleh ahli sitologi.

Ini juga salah satu alat diagnostik utama untuk mendeteksi kanker. Ujian ginekologi tahunan seorang wanita hampir selalu melibatkan pap smear, mengumpulkan jaringan yang dianalisis pada struktur selular untuk mendeteksi formasi awal sel kanker. Deteksi dini dapat menyebabkan tingkat kelangsungan hidup yang lebih besar. Demikian pula, biopsi jarum benjolan di pay udara atau di tempat lain dapat mendeteksi sel-sel kanker dan memberikan sarana yang sangat baik untuk diagnosis.

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